The Creator's Triune are the strongest creations of Master Hand and Crazy Hand, and are split into seven groups. The Light Triune consists of Naruto Uzumaki, Goku, and Sonic the Hedgehog, the Dark Triune consists of Sasuke Uchiha, Yami Bakura, and Mechtavius Destroyer, the Melee Triune consists of Bowser, Ganondorf, and Mewtwo, the Controller Triune consists of Marth, Ridley, and Kirby, the Descendants Triune consists of Princess Peach, Gwen Tennyson, and Mecha Sally, the Fated Triune consists of Mario, Link, and Lucario, and the Ultimate Triune consists of Shadow the Hedgehog, Roy, and Midna. As the strongest creations of the hands, the Creator's Triune have the power to control the entire multiverse.
- Naruto Uzumaki (Light Triune)
- Goku (Light Triune)
- Sonic the Hedgehog (Light Triune)
- Sasuke Uchiha (Dark Triune)
- Yami Bakura (Dark Triune)
- Mechtavius Destroyer (Dark Triune)
- Bowser (Melee Triune)
- Ganondorf (Melee Triune)
- Mewtwo (Melee Triune)
- Marth (Controller Triune)
- Ridley (Controller Triune)
- Kirby (Controller Triune)
- Princess Peach (Descendants Triune)
- Gwen Tennyson (Descendants Triune)
- Mecha Sally (Descendants Triune)
- Mario (Fated Triune)
- Link (Fated Triune)
- Lucario (Fated Triune)
- Shadow the Hedgehog (Ultimate Triune)
- Roy (Ultimate Triune)
- Midna (Ultimate Triune)
- Naruto and Sasuke are the only Creator's Triune to hail from the same series.
- Mechtavius Destroyer is the only Creator's Triune to be a combined form.